SLiM

SLiM ("Selection on Linked Mutations") is software designed for conducting forward-in-time genetic simulations of eco-evolutionary scenarios. It allows researchers to simulate complex population genetics models, accommodating both Wright-Fisher and non-Wright-Fisher models. Over a thousand scientific papers have cited one of the SLiM release publications (and, presumably, used the software for simulations), according to GoogleScholar (in particular version 3[1]).

SLiM supports various evolutionary processes, including mutation, recombination, migration, and genetic drift,[2] selection on fecundity or survival,[3] and is designed to enable users to explore the dynamics of genomes under different selective pressures and demographic events of one or multiple populations and species.[4]

The SLiM also offers a scripting language, Eidos, which provides customization options for defining evolutionary parameters and interactions within and between populations. Almost all information regarding Eidos and SLiM are available in the SLiM[5] and Eidos manuals.[6]

References

  1. ^ Haller, Benjamin C.; Messer, Philipp W. (2019). "SLiM 3: forward genetic simulations beyond the Wright–Fisher model". Molecular Biology and Evolution. 36 (3): 632–637. doi:10.1093/molbev/msy228. PMC 6389312. PMID 30517680.
  2. ^ Haller, Benjamin C.; Messer, Philipp W. (2017). "SLiM 2: flexible, interactive forward genetic simulations". Molecular Biology and Evolution. 34 (1): 230–240. doi:10.1093/molbev/msw211. PMID 27702775.
  3. ^ Haller, Benjamin C.; Messer, Philipp W. (2019). "SLiM 3: forward genetic simulations beyond the Wright–Fisher model". Molecular Biology and Evolution. 36 (3): 632–637. doi:10.1093/molbev/msy228. PMC 6389312. PMID 30517680.
  4. ^ Haller, Benjamin C.; Messer, Philipp W. (2023). "SLiM 4: multispecies eco-evolutionary modeling". The American Naturalist. 201 (5): E127–E139. doi:10.1086/724133. PMC 10793872. PMID 37130229.
  5. ^ Haller, B.C.; Messer, P.W. (2016). "SLiM: An Evolutionary Simulation Framework" (PDF). Retrieved 26 August 2024.
  6. ^ Haller, B.C. (2016). "Eidos: A Simple Scripting Language" (PDF). Retrieved 26 August 2024.


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