ERCC3

ERCC3
Structures disponibles PDB Recherche d'orthologue : PDBe RCSB Identifiants PDB 4ERN, 5IY9, 5IVW, 5IY7, 5IY8, 5IY6
Identifiants
Alias	ERCC3
IDs externes	OMIM: 133510 MGI: 95414 HomoloGene: 96 GeneCards: ERCC3
Position du gène (humain) Chr. Chromosome 2 humain[1] Locus 2q14.3 Début 127,257,290 bp[1] Fin 127,294,166 bp[1]
Position du gène (souris) Chr. Chromosome 18 (souris)[2] Locus 18|18 B1 Début 32,373,353 bp[2] Fin 32,403,204 bp[2]
Expression génique Bgee Humain Souris (orthologue) Fortement exprimé dans nerf sural right hemisphere of cerebellum right uterine tube muqueuse gastrique gonade granulocyte éminence ganglionnaire body of uterus anté-hypophyse endocol Fortement exprimé dans spermatide corpuscule rénal granulocyte endothelial cell of lymphatic vessel ventricular zone épiblaste tail of embryo medullary collecting duct lumbar spinal ganglion Vésicule vitelline Plus de données d'expression de référence BioGPS Plus de données d'expression de référence
Gene Ontology Fonction moléculaire protein C-terminus binding liaison nucléotide DNA helicase activity protein kinase activity activité hydrolase ATP-dependent activity, acting on DNA protein N-terminus binding 3'-5' DNA helicase activity liaison ATP damaged DNA binding liaison ADN transcription factor binding liaison protéique helicase activity RNA polymerase II CTD heptapeptide repeat kinase activity activité ATPase DNA translocase activity Composant cellulaire transcription factor TFIIH core complex noyau nucléoplasme transcription factor TFIIH holo complex transcription factor TFIID complex nucleotide-excision repair factor 3 complex transcription preinitiation complex Processus biologique response to hypoxia termination of RNA polymerase I transcription embryonic organ development transcription, DNA-templated response to UV 7-methylguanosine mRNA capping nucleotide-excision repair, DNA incision regulation of mitotic cell cycle phase transition apoptose positive regulation of apoptotic process phosphorylation des protéines différenciation des cellules ciliées response to oxidative stress UV protection cellular response to DNA damage stimulus transcription initiation from RNA polymerase II promoter global genome nucleotide-excision repair protein localization transcription elongation from RNA polymerase II promoter regulation of transcription, DNA-templated positive regulation of transcription by RNA polymerase II DNA topological change transcription initiation from RNA polymerase I promoter transcription by RNA polymerase II transcription-coupled nucleotide-excision repair Réparation par excision de nucléotides nucleotide-excision repair, preincision complex stabilization réparation de l'ADN viral process nucleotide-excision repair, preincision complex assembly nucleotide-excision repair, DNA incision, 5'-to lesion nucleotide-excision repair, DNA duplex unwinding regulation of mitotic recombination promoter clearance from RNA polymerase II promoter transcription open complex formation at RNA polymerase II promoter regulation of transposition, RNA-mediated phosphorylation of RNA polymerase II C-terminal domain regulation of RNA polymerase II regulatory region sequence-specific DNA binding nucleotide-excision repair, DNA incision, 3'-to lesion transcription elongation from RNA polymerase I promoter Sources:Amigo / QuickGO
Orthologues Espèces Homme Souris Entrez 2071 13872 Ensembl ENSG00000163161 ENSMUSG00000024382 UniProt P19447 P49135 RefSeq (mRNA) NM_000122 NM_001303416 NM_001303418 NM_133658 RefSeq (protéine) NP_000113 NP_001290345 NP_001290347 NP_598419 Localisation (UCSC) Chr 2: 127.26 – 127.29 Mb Chr 18: 32.37 – 32.4 Mb Publication PubMed [3] [4]
Wikidata
Voir/Editer Humain Voir/Editer Souris

ERCC3 est un gène situé sur le chromosome 2 humain^[5].

• Xeroderma pigmentosum^[6]
• Complexe Xeroderma pigmentosum-syndrome de Cockayne
• Trichothiodystrophie

• Portail de la biologie cellulaire et moléculaire
• Portail de la médecine