HRAS

HRAS
Structures disponibles
PDB	Recherche d'orthologue : PDBe RCSB
Identifiants PDB
	121P, 1AA9, 1AGP, 1BKD, 1CLU, 1CRP, 1CRQ, 1CRR, 1CTQ, 1GNP, 1GNQ, 1GNR, 1HE8, 1IAQ, 1IOZ, 1JAH, 1JAI, 1K8R, 1LF0, 1LF5, 1LFD, 1NVU, 1NVV, 1NVW, 1NVX, 1P2S, 1P2T, 1P2U, 1P2V, 1PLJ, 1PLK, 1PLL, 1Q21, 1QRA, 1RVD, 1WQ1, 1XCM, 1XD2, 1XJ0, 1ZVQ, 1ZW6, 221P, 2C5L, 2CE2, 2CL0, 2CL6, 2CL7, 2CLC, 2CLD, 2EVW, 2LCF, 2LWI, 2Q21, 2QUZ, 2RGA, 2RGB, 2RGC, 2RGD, 2RGE, 2RGG, 2UZI, 2VH5, 2X1V, 3DDC, 3I3S, 3K8Y, 3K9L, 3K9N, 3KKM, 3KKN, 3KUD, 3L8Y, 3L8Z, 3LBH, 3LBI, 3LBN, 3LO5, 3OIU, 3OIV, 3OIW, 3RRY, 3RRZ, 3RS0, 3RS2, 3RS3, 3RS4, 3RS5, 3RS7, 3RSL, 3RSO, 421P, 4DLR, 4DLS, 4DLT, 4DLU, 4DLV, 4DLW, 4DLX, 4DLY, 4DLZ, 4EFL, 4EFM, 4EFN, 4G0N, 4G3X, 4K81, 4Q21, 521P, 5P21, 621P, 6Q21, 721P, 821P, 4L9S, 4L9W, 4NYI, 4NYJ, 4NYM, 4URU, 4URV, 4URW, 4URX, 4URY, 4URZ, 4US0, 4US1, 4US2, 2N42, 2N46, 4XVQ, 4XVR, 4RSG, 5B30
Identifiants
Alias	HRAS
IDs externes	OMIM: 190020 MGI: 96224 HomoloGene: 55890 GeneCards: HRAS
Position du gène (humain)
Chr.	Chromosome 11 humain
Fin	537,321 bp
Position du gène (souris)
Chr.	Chromosome 7 (souris)
Fin	140,773,918 bp
Expression génique
	Fortement exprimé dans
	skin of abdomen; ; skin of leg; ; putamen; ; noyau caudé; ; noyau accumbens; ; hypothalamus; ; lobe temporal; ; amygdale; ; right hemisphere of cerebellum; ; substantia nigra;
	Fortement exprimé dans
	dentate gyrus of hippocampal formation granule cell; ; lèvre; ; molaire; ; gyrus frontal supérieur; ; œsophage; ; fetal liver hematopoietic progenitor cell; ; Vésicule vitelline; ; cortex entorhinal; ; Cortex périrhinal; ; muscle de la cuisse;
	Plus de données d'expression de référence
	; ; ; ;
	Plus de données d'expression de référence
Gene Ontology
Fonction moléculaire	liaison nucléotide; protein C-terminus binding; liaison protéique; GTPase activity; GTP binding; GDP binding;
Composant cellulaire	cytoplasme; cytosol; appareil de Golgi; intracellular membrane-bounded organelle; membrane; Golgi membrane; membrane plasmique; perinuclear region of cytoplasm; noyau; glutamatergic synapse;
Processus biologique	negative regulation of neuron apoptotic process; defense response to protozoan; positive regulation of protein phosphorylation; regulation of long-term neuronal synaptic plasticity; endocytose; positive regulation of MAP kinase activity; positive regulation of miRNA metabolic process; positive regulation of epithelial cell proliferation; positive regulation of ruffle assembly; mitotic cell cycle checkpoint signaling; positive regulation of cell migration; ephrin receptor signaling pathway; positive regulation of wound healing; positive regulation of Ras protein signal transduction; positive regulation of interferon-gamma production; stimulatory C-type lectin receptor signaling pathway; positive regulation of JNK cascade; negative regulation of gene expression; MAPK cascade; intrinsic apoptotic signaling pathway; positive regulation of GTPase activity; chimiotaxie; cell surface receptor signaling pathway; positive regulation of gene expression; negative regulation of GTPase activity; positive regulation of cell population proliferation; positive regulation of ERK1 and ERK2 cascade; morphogenèse d'un organe animal; T-helper 1 type immune response; Ras protein signal transduction; prolifération cellulaire; T cell receptor signaling pathway; positive regulation of actin cytoskeleton reorganization; positive regulation of MAPK cascade; negative regulation of cell population proliferation; positive regulation of transcription by RNA polymerase II; transduction de signal; apoptose; small GTPase mediated signal transduction; sénescence cellulaire; response to isolation stress; cellular response to gamma radiation; positive regulation of DNA replication; positive regulation of phospholipase C activity; protein heterooligomerization; positive regulation of protein targeting to membrane; regulation of neurotransmitter receptor localization to postsynaptic specialization membrane;
	Sources:Amigo / QuickGO
Orthologues
	3265
	15461
	ENSG00000276536; ENSG00000174775
	ENSMUSG00000025499
	P01112
	Q61411
	NM_001130442; NM_005343; NM_176795; NM_001318054
	NM_001130443; NM_001130444; NM_008284
	NP_001123914; NP_001304983; NP_005334; NP_789765
	NP_001123915; NP_001123916; NP_032310
	Wikidata
Voir/Editer Humain	Voir/Editer Souris