RPA2

RPA2
Structures disponibles
PDB	Recherche d'orthologue : PDBe RCSB
Identifiants PDB
	1DPU, 1L1O, 1QUQ, 1Z1D, 2PI2, 2PQA, 2Z6K, 3KDF, 4MQV, 4OU0
Identifiants
Alias	RPA2
IDs externes	OMIM: 179836 MGI: 1339939 HomoloGene: 37712 GeneCards: RPA2
Position du gène (humain)
Chr.	Chromosome 1 humain
Fin	27,914,746 bp
Position du gène (souris)
Chr.	Chromosome 4 (souris)
Fin	132,506,063 bp
Expression génique
	Fortement exprimé dans
	ventricular zone; ; granulocyte; ; éminence ganglionnaire; ; right testis; ; left testis; ; muscle gastrocnémien; ; tendon calcanéen; ; right uterine tube; ; gonade; ; muscle tibial antérieur;
	Fortement exprimé dans
	somite; ; fetal liver hematopoietic progenitor cell; ; ligne primitive; ; embryon; ; ventricular zone; ; mandibular prominence; ; endocardial cushion; ; paroi abdominale; ; feuillet embryonnaire; ; Ectoderme;
	Plus de données d'expression de référence
	Plus de données d'expression de référence
Gene Ontology
Fonction moléculaire	liaison ADN; protein N-terminus binding; single-stranded DNA binding; damaged DNA binding; liaison protéique; liaison enzymatique; protein phosphatase binding; ubiquitin protein ligase binding; G-rich strand telomeric DNA binding; double-stranded DNA binding; sequence-specific DNA binding;
Composant cellulaire	site of double-strand break; PML body; nucléoplasme; télomère; protéine de réplication A; chromatine; noyau; corps nucléaire; condensed nuclear chromosome;
Processus biologique	nucleotide-excision repair, DNA gap filling; DNA recombination; interstrand cross-link repair; regulation of double-strand break repair via homologous recombination; error-free translesion synthesis; phase G1; error-prone translesion synthesis; cellular response to DNA damage stimulus; réplication de l'ADN; mitotic G1 DNA damage checkpoint signaling; regulation of DNA damage checkpoint; regulation of cellular response to heat; Mismatch repair; translesion synthesis; transcription-coupled nucleotide-excision repair; nucleotide-excision repair, DNA incision; base-excision repair; Réparation par excision de nucléotides; nucleotide-excision repair, preincision complex stabilization; regulation of signal transduction by p53 class mediator; réparation de l'ADN; double-strand break repair via homologous recombination; nucleotide-excision repair, preincision complex assembly; nucleotide-excision repair, DNA incision, 5'-to lesion; nucleotide-excision repair, DNA incision, 3'-to lesion; protein localization to chromosome; maintien des télomères; maintien des télomères par réplication semi-conservative; G1/S transition of mitotic cell cycle; telomere maintenance via recombination; DNA topological change; DNA unwinding involved in DNA replication; mitotic recombination; telomere maintenance via telomerase; reciprocal meiotic recombination; heteroduplex formation; positive regulation of helicase activity;
	Sources:Amigo / QuickGO
Orthologues
	6118
	19891
	ENSG00000117748
	ENSMUSG00000028884
	P15927
	Q62193
	NM_001286076; NM_001297558; NM_002946; NM_001355128; NM_001355129
	NM_011284
	NP_001273005; NP_001284487; NP_002937; NP_001342057; NP_001342058
	n/a
	Wikidata
Voir/Editer Humain	Voir/Editer Souris