SLC7A11

SLC7A11
Identifiants
Alias	SLC7A11
IDs externes	OMIM: 607933 MGI: 1347355 HomoloGene: 22684 GeneCards: SLC7A11
Position du gène (humain)
Chr.	Chromosome 4 humain
Fin	138,242,349 bp
Position du gène (souris)
Chr.	Chromosome 3 (souris)
Fin	50,398,063 bp
Expression génique
	Fortement exprimé dans
	nerf optique; ; stromal cell of endometrium; ; external globus pallidus; ; internal globus pallidus; ; cortex entorhinal; ; cartilage tissue; ; cellule endothéliale; ; bulbe rachidien; ; gingival epithelium; ; noyau vestibulaire supérieur;
	Fortement exprimé dans
	secondary oocyte; ; primary oocyte; ; granulocyte; ; zygote; ; choroidal fissure; ; lumbar subsegment of spinal cord; ; dentate gyrus of hippocampal formation granule cell; ; epithelium of lens; ; endothelial cell of lymphatic vessel; ; thymus;
	Plus de données d'expression de référence
	; ; ; ;
	Plus de données d'expression de référence
Gene Ontology
Fonction moléculaire	cystine:glutamate antiporter activity; liaison protéique; transmembrane transporter activity; L-amino acid transmembrane transporter activity;
Composant cellulaire	integral component of membrane; réticulum endoplasmique rugueux; membrane; intracellular membrane-bounded organelle; membrane plasmique; surface cellulaire; cytosquelette; integral component of plasma membrane; brush border membrane; astrocyte projection;
Processus biologique	response to nicotine; response to oxidative stress; développement cérébral; lens fiber cell differentiation; Agrégation plaquettaire; amino acid transport; réponse à une substance toxique; leukocyte migration; transport transmembranaire; L-glutamate transmembrane transport; glutathione metabolic process; visual learning; response to organic cyclic compound; ventricular system development; striatum development; adult behavior; regulation of neutrophil apoptotic process; cellular response to oxidative stress; glutathione transmembrane transport; regulation of cell population proliferation; regulation of melanin biosynthetic process; lung alveolus development; modulation of chemical synaptic transmission; regulation of synapse organization; regulation of protein transport; response to redox state; Membre chiridien; organic substance transport; glutamate homeostasis; L-glutamate import across plasma membrane; dipeptide import across plasma membrane; regulation of cellular response to oxidative stress; regulation of cysteine metabolic process; negative regulation of oxidative stress-induced neuron death; regulation of glutathione biosynthetic process; regulation of AMPA glutamate receptor clustering; regulation of glutamate metabolic process;
	Sources:Amigo / QuickGO
Orthologues
	23657
	26570
	ENSG00000151012
	ENSMUSG00000027737
	Q9UPY5
	Q9WTR6
	NM_014331
	NM_011990
	NP_055146
	NP_036120
	Wikidata
Voir/Editer Humain	Voir/Editer Souris