DNAJB2
DNAJB2 (DnaJ heat shock protein family (Hsp40) member B2) هوَ بروتين يُشَفر بواسطة جين DNAJB2 في الإنسان.[1][2][3]
الوظيفة
الأهمية السريرية
المراجع
- ^ Cheetham ME، Brion JP، Anderton BH (يوليو 1992). "Human homologues of the bacterial heat-shock protein DnaJ are preferentially expressed in neurons". Biochem J. 284 ( Pt 2) ع. Pt 2: 469–76. PMC:1132662. PMID:1599432.
- ^ "Entrez Gene: DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2". مؤرشف من الأصل في 2010-12-05.
- ^ Chapple JP، Hardcastle AJ، Kurzik-Dumke U، Collier DA، Cheetham ME (أكتوبر 1999). "Assignment of the neuronal cochaperone, HSJ1, to human chromosome bands 2q32→q34 between D2S295 and D2S339 by in situ hybridization and somatic cell and radiation hybrids". Cytogenet Cell Genet. ج. 86 ع. 1: 62–3. DOI:10.1159/000015411. PMID:10516435.
قراءة متعمقة
- Bonaldo MF، Lennon G، Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. ج. 6 ع. 9: 791–806. DOI:10.1101/gr.6.9.791. PMID:8889548.
- Ohtsuka K، Hata M (2001). "Mammalian HSP40/DNAJ homologs: cloning of novel cDNAs and a proposal for their classification and nomenclature". Cell Stress Chaperones. ج. 5 ع. 2: 98–112. DOI:10.1379/1466-1268(2000)005<0098:MHDHCO>2.0.CO;2. PMC:312896. PMID:11147971.
- Wistow G، Bernstein SL، Wyatt MK (2002). "Expressed sequence tag analysis of human RPE/choroid for the NEIBank Project: over 6000 non-redundant transcripts, novel genes and splice variants". Mol. Vis. ج. 8: 205–20. PMID:12107410.
- Strausberg RL، Feingold EA، Grouse LH (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. ج. 99 ع. 26: 16899–903. DOI:10.1073/pnas.242603899. PMC:139241. PMID:12477932.
- Chapple JP، Cheetham ME (2003). "The chaperone environment at the cytoplasmic face of the endoplasmic reticulum can modulate rhodopsin processing and inclusion formation". J. Biol. Chem. ج. 278 ع. 21: 19087–94. DOI:10.1074/jbc.M212349200. PMID:12754272.
{{استشهاد بدورية محكمة}}: صيانة الاستشهاد: دوي مجاني غير معلم (link) - Janket ML، Manickam P، Majumder B (2004). "Differential regulation of host cellular genes by HIV-1 viral protein R (Vpr): cDNA microarray analysis using isogenic virus". Biochem. Biophys. Res. Commun. ج. 314 ع. 4: 1126–32. DOI:10.1016/j.bbrc.2004.01.008. PMID:14751250.
- Hillman RT، Green RE، Brenner SE (2005). "An unappreciated role for RNA surveillance". Genome Biol. ج. 5 ع. 2: R8. DOI:10.1186/gb-2004-5-2-r8. PMC:395752. PMID:14759258.
{{استشهاد بدورية محكمة}}: صيانة الاستشهاد: دوي مجاني غير معلم (link) - Colland F، Jacq X، Trouplin V (2004). "Functional Proteomics Mapping of a Human Signaling Pathway". Genome Res. ج. 14 ع. 7: 1324–32. DOI:10.1101/gr.2334104. PMC:442148. PMID:15231748.
- Gerhard DS، Wagner L، Feingold EA (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. ج. 14 ع. 10B: 2121–7. DOI:10.1101/gr.2596504. PMC:528928. PMID:15489334.
- Westhoff B، Chapple JP، van der Spuy J (2005). "HSJ1 is a neuronal shuttling factor for the sorting of chaperone clients to the proteasome". Curr. Biol. ج. 15 ع. 11: 1058–64. DOI:10.1016/j.cub.2005.04.058. PMID:15936278.
- Rual JF، Venkatesan K، Hao T (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. ج. 437 ع. 7062: 1173–8. DOI:10.1038/nature04209. PMID:16189514.
- Borrell-Pagès M، Canals JM، Cordelières FP (2006). "Cystamine and cysteamine increase brain levels of BDNF in Huntington disease via HSJ1b and transglutaminase". J. Clin. Invest. ج. 116 ع. 5: 1410–24. DOI:10.1172/JCI27607. PMC:1430359. PMID:16604191.
- Adaimy L، Chouery E، Megarbane H (2007). "Mutation in WNT10A Is Associated with an Autosomal Recessive Ectodermal Dysplasia: The Odonto-onycho-dermal Dysplasia". Am. J. Hum. Genet. ج. 81 ع. 4: 821–8. DOI:10.1086/520064. PMC:1973944. PMID:17847007.