MYO15B (англ. Myosin XVB) — білок, який кодується однойменним геном, розташованим у людей на 17-й хромосомі.[2] Довжина поліпептидного ланцюга білка становить 1 530 амінокислот, а молекулярна маса — 167 118[3].
Послідовність амінокислот
| 10
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20
|
|
30
|
|
40
|
|
50
|
| MKEASGVGGG
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|
HSPMCPPHCH
|
|
MPPGPAGEWP
|
|
GATVQQPRQR
|
|
APTALLQPDA
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| AGPGGGGVSA
|
|
GVAVLGACPS
|
|
ASEGVLPRPP
|
|
GRSAPQPPEY
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|
PGRPDMAVPG
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| WSAMVRSRLT
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|
ATSTSQATDH
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|
TFLQKSHYHH
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|
GDHPSYAKPR
|
|
LPLPVFTVRH
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| YAGTVTYQVH
|
|
KFLNRNRDQL
|
|
DPAVVEMLGQ
|
|
SQLQLVGSLF
|
|
QEAEPQSRGG
|
| RGRPTLASRF
|
|
QQALEDLIAR
|
|
LGRSHVYFIQ
|
|
CLTPNPGKLP
|
|
GLFDVGHVTE
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| QLHQAAILEA
|
|
VGTRSANFPV
|
|
RVPFEAFLAS
|
|
FQALGSEGQE
|
|
DLSDREKCGA
|
| VLSQVLGAES
|
|
PLYHLGATKV
|
|
LLQEQGWQRL
|
|
EELRDQQRSQ
|
|
ALVDLHRSFH
|
| TCISRQRVLP
|
|
RMQARMRGFQ
|
|
ARKRYLRRRA
|
|
ALGQLNTILL
|
|
VAQPLLQRRQ
|
| RLQLGRWQGW
|
|
HSSERALERV
|
|
PSMELGRLEI
|
|
PAELAVMLKT
|
|
AESHRDALAG
|
| SITECLPPEV
|
|
PARPSLTLPA
|
|
DIDLFPFSSF
|
|
VAIGFQEPSL
|
|
PRPGQPLAKP
|
| LTQLDGDNPQ
|
|
RALDINKVML
|
|
RLLGDGSLES
|
|
WQRQIMGAYL
|
|
VRQGQCWPGL
|
| RNELFSQLVA
|
|
QLWQNPDEQQ
|
|
SQRGWALMAV
|
|
LLSAFPPLPV
|
|
LQKPLLKFVS
|
| DQAPRGMAAL
|
|
CQHKLLGALE
|
|
QSQLASGATR
|
|
AHPPTQLEWL
|
|
AGWRRGRMAL
|
| DVFTFSEECY
|
|
SAEVESWTTG
|
|
EQLAGWILQS
|
|
RGLEAPPRGW
|
|
SVSLHSRDAW
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| QDLAGCDFVL
|
|
DLISQTEDLG
|
|
DPARPRSYPI
|
|
TPLGSAEAIP
|
|
LAPGIQAPSL
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| PPGPPPGPAP
|
|
TLPSRDHTGE
|
|
VQRSGSLDGF
|
|
LDQIFQPVIS
|
|
SGLSDLEQSW
|
| ALSSRMKGGG
|
|
AIGPTQQGYP
|
|
MVYPGMIQMP
|
|
AYQPGMVPAP
|
|
MPMMPAMGTV
|
| PAMPAMVVPP
|
|
QPPLPSLDAG
|
|
QLAVQQQNFI
|
|
QQQALILAQQ
|
|
MTAQAMSLSL
|
| EQQMQQRQQQ
|
|
ARASEAASQA
|
|
SPSAVTSKPR
|
|
KPPTPPEKPQ
|
|
RDLGSEGGCL
|
| RETSEEAEDR
|
|
PYQPKSFQQK
|
|
RNYFQRMGQP
|
|
QITVRTMKPP
|
|
AKVHIPQGEA
|
| QEEEEEEEEE
|
|
EEQEEQEVET
|
|
RAVPSPPPPP
|
|
IVKKPLKQGG
|
|
AKAPKEAEAE
|
| PAKETAAKGH
|
|
GQGPAQGRGT
|
|
VVRSSDSKPK
|
|
RPQPSREIGN
|
|
IIRMYQSRPG
|
| PVPVPVQPSR
|
|
PPKAFLRKID
|
|
PKDEALAKLG
|
|
INGAHSSPPM
|
|
LSPSPGKGPP
|
| PAVAPRPKAP
|
|
LQLGPSSSIK
|
|
EKQGPLLDLF
|
|
GQKLPIAHTP
|
|
PPPPAPPLPL
|
| PEDPGTLSAE
|
|
RRCLTQPVED
|
|
QGVSTQLLAP
|
|
SGSVCFSYTG
|
|
TPWKLFLRKE
|
| VFYPRENFSH
|
|
PYYLRLLCEQ
|
|
ILRDTFSESC
|
|
IRISQNERRK
|
|
MKDLLGGLEV
|
| DLDSLTTTED
|
|
SVKKRIVVAA
|
|
RDNWANYFSR
|
|
FFPVSGESGS
|
|
DVQLLAVSHR
|
| GLRLLKVTQG
|
|
PGLRPDQLKI
|
|
LCSYSFAEVL
|
|
GVECRGGSTL
|
|
ELSLKSEQLV
|
| LHTARARAIE
|
|
ALVELFLNEL
|
|
KKDSGYVIAL
|
|
RSYITDNCSL
|
|
LSFHRGDLIK
|
| LLPVATLEPG
|
|
WQFGSAGGRS
|
|
GLFPADIVQP
|
|
AAAPDFSFSK
|
|
EQRSGWHKGQ
|
| LSNGEPGLAR
|
|
WDRASEVRKM
|
|
GEGQAEARPA
|
Локалізований у цитоплазмі.
Література
- Boger E. T., Sellers J. R., Friedman T. B. (2001). Human myosin XVBP is a transcribed pseudogene. J. Muscle Res. Cell Motil. 22: 477—483. PMID 11964073 doi:10.1023/A:1014507705858
- Nagase T., Nakayama M., Nakajima D., Kikuno R., Ohara O. (2001). Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. DNA Res. 8: 8595. PMID 11347906 doi:10.1093/dnares/8.2.85
- Berg J. S., Powell B. C., Cheney R. E. (2001). A millennial myosin census. journal=Mol. Biol. Cell. 12: 780—794. ; PMID 11294886 doi:10.1091/mbc.12.4.780
Примітки
Див. також