SERPINB9
SERPINB9 (Serpin family B member 9) هوَ بروتين يُشَفر بواسطة جين SERPINB9 في الإنسان.[1][2][3]
الوظيفة
الأهمية السريرية
المراجع
- ^ Sun J، Stephens R، Mirza G، Kanai H، Ragoussis J، Bird PI (فبراير 1999). "A serpin gene cluster on human chromosome 6p25 contains PI6, PI9 and ELANH2 which have a common structure almost identical to the 18q21 ovalbumin serpin genes". Cytogenet Cell Genet. ج. 82 ع. 3–4: 273–7. DOI:10.1159/000015118. PMID:9858835.
- ^ "Entrez Gene: SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9". مؤرشف من الأصل في 2010-12-05.
- ^ Sprecher CA، Morgenstern KA، Mathewes S، Dahlen JR، Schrader SK، Foster DC، Kisiel W (يناير 1996). "Molecular cloning, expression, and partial characterization of two novel members of the ovalbumin family of serine proteinase inhibitors". J Biol Chem. ج. 270 ع. 50: 29854–61. DOI:10.1074/jbc.270.50.29854. PMID:8530382.
{{استشهاد بدورية محكمة}}: صيانة الاستشهاد: دوي مجاني غير معلم (link)
قراءة متعمقة
- Sun J، Bird CH، Sutton V، وآخرون (1996). "A cytosolic granzyme B inhibitor related to the viral apoptotic regulator cytokine response modifier A is present in cytotoxic lymphocytes". J. Biol. Chem. ج. 271 ع. 44: 27802–9. DOI:10.1074/jbc.271.44.27802. PMID:8910377.
{{استشهاد بدورية محكمة}}: صيانة الاستشهاد: دوي مجاني غير معلم (link) - Annand RR، Dahlen JR، Sprecher CA، وآخرون (1999). "Caspase-1 (interleukin-1beta-converting enzyme) is inhibited by the human serpin analogue proteinase inhibitor 9". Biochem. J. 342 Pt 3 ع. 3: 655–65. DOI:10.1042/0264-6021:3420655. PMC:1220507. PMID:10477277.
- Kanamori H، Krieg S، Mao C، وآخرون (2000). "Proteinase inhibitor 9, an inhibitor of granzyme B-mediated apoptosis, is a primary estrogen-inducible gene in human liver cells". J. Biol. Chem. ج. 275 ع. 8: 5867–73. DOI:10.1074/jbc.275.8.5867. PMID:10681578.
{{استشهاد بدورية محكمة}}: صيانة الاستشهاد: دوي مجاني غير معلم (link) - Bladergroen BA، Strik MC، Bovenschen N، وآخرون (2001). "The granzyme B inhibitor, protease inhibitor 9, is mainly expressed by dendritic cells and at immune-privileged sites". J. Immunol. ج. 166 ع. 5: 3218–25. DOI:10.4049/jimmunol.166.5.3218. PMID:11207275.
- Buzza MS، Hirst CE، Bird CH، وآخرون (2001). "The granzyme B inhibitor, PI-9, is present in endothelial and mesothelial cells, suggesting that it protects bystander cells during immune responses". Cell. Immunol. ج. 210 ع. 1: 21–9. DOI:10.1006/cimm.2001.1806. PMID:11485349.
- Hirst CE، Buzza MS، Sutton VR، وآخرون (2002). "Perforin-independent expression of granzyme B and proteinase inhibitor 9 in human testis and placenta suggests a role for granzyme B-mediated proteolysis in reproduction". Mol. Hum. Reprod. ج. 7 ع. 12: 1133–42. DOI:10.1093/molehr/7.12.1133. PMID:11719590.
- Tanaka K، Harashima N، Niiya F، وآخرون (2002). "Serine proteinase inhibitor 9 can be recognized by cytotoxic T lymphocytes of epithelial cancer patients". Jpn. J. Cancer Res. ج. 93 ع. 2: 198–208. DOI:10.1111/j.1349-7006.2002.tb01259.x. PMID:11856484.
- ten Berge RL، Meijer CJ، Dukers DF، وآخرون (2002). "Expression levels of apoptosis-related proteins predict clinical outcome in anaplastic large cell lymphoma". Blood. ج. 99 ع. 12: 4540–6. DOI:10.1182/blood.V99.12.4540. PMID:12036886.
- Strausberg RL، Feingold EA، Grouse LH، وآخرون (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. ج. 99 ع. 26: 16899–903. DOI:10.1073/pnas.242603899. PMC:139241. PMID:12477932.
- Hirst CE، Buzza MS، Bird CH، وآخرون (2003). "The intracellular granzyme B inhibitor, proteinase inhibitor 9, is up-regulated during accessory cell maturation and effector cell degranulation, and its overexpression enhances CTL potency". J. Immunol. ج. 170 ع. 2: 805–15. DOI:10.4049/jimmunol.170.2.805. PMID:12517944.
- Rowshani AT، Florquin S، Bemelman F، وآخرون (2005). "Hyperexpression of the granzyme B inhibitor PI-9 in human renal allografts: a potential mechanism for stable renal function in patients with subclinical rejection". Kidney Int. ج. 66 ع. 4: 1417–22. DOI:10.1111/j.1523-1755.2004.00903.x. PMID:15458434.
- Gerhard DS، Wagner L، Feingold EA، وآخرون (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. ج. 14 ع. 10B: 2121–7. DOI:10.1101/gr.2596504. PMC:528928. PMID:15489334.
- Mahrus S، Kisiel W، Craik CS (2005). "Granzyme M is a regulatory protease that inactivates proteinase inhibitor 9, an endogenous inhibitor of granzyme B". J. Biol. Chem. ج. 279 ع. 52: 54275–82. DOI:10.1074/jbc.M411482200. PMID:15494398.
{{استشهاد بدورية محكمة}}: صيانة الاستشهاد: دوي مجاني غير معلم (link) - Classen CF، Ushmorov A، Bird P، Debatin KM (2006). "The granzyme B inhibitor PI-9 is differentially expressed in all main subtypes of pediatric acute lymphoblastic leukemias". Haematologica. ج. 89 ع. 11: 1314–21. PMID:15531453.
- Bruneel A، Labas V، Mailloux A، وآخرون (2006). "Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis". Proteomics. ج. 5 ع. 15: 3876–84. DOI:10.1002/pmic.200401239. PMID:16130169.
- van Houdt IS، Oudejans JJ، van den Eertwegh AJ، وآخرون (2005). "Expression of the apoptosis inhibitor protease inhibitor 9 predicts clinical outcome in vaccinated patients with stage III and IV melanoma". Clin. Cancer Res. ج. 11 ع. 17: 6400–7. DOI:10.1158/1078-0432.CCR-05-0306. PMID:16144945.
- Stelzl U، Worm U، Lalowski M، وآخرون (2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell. ج. 122 ع. 6: 957–68. DOI:10.1016/j.cell.2005.08.029. PMID:16169070.
- Rual JF، Venkatesan K، Hao T، وآخرون (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. ج. 437 ع. 7062: 1173–8. DOI:10.1038/nature04209. PMID:16189514.